心臟成纖維細胞為心肌細胞提供結(jié)構(gòu)支持，并負責(zé)在生長和病理生理條件下心肌細胞外基質(zhì)的合成。CF是心肌損傷反應(yīng)的重要細胞成分和旁分泌生長因子的來源。CF的增殖和基質(zhì)合成對于心肌梗塞、心肌纖維化部位瘢痕形成具有重要作用。CF的培養(yǎng)已被廣泛應(yīng)用為生理（運動）和病理（高血壓）應(yīng)激下心臟基質(zhì)重塑研究的模型。CF的培養(yǎng)已被廣泛應(yīng)用為生理（運動）和病理（高血壓）應(yīng)激下心臟基質(zhì)重塑研究的模型。CF通過間隙連接施加電緊張，影響心肌細胞的電耦合性形式。這些電耦合被認為在心房復(fù)雜的分流電描位點發(fā)生中起重要作用，因此是研究房顫的一個**模型。
Sciencell研究實驗室的HCF-aa是從人胎兒心房分離得到的，原代凍存，冰凍運輸。每管細胞密度超過5×10^5/ml。細胞特性經(jīng)纖維粘連蛋白免疫熒光鑒定。本細胞經(jīng)檢測不含HIV-1、HBV、HCV、支原體、細菌、酵母菌和真菌。如采用ScienCell 實驗室特制的培養(yǎng)基，可保證此細胞15倍增增殖。
推薦培養(yǎng)基：內(nèi)皮細胞培養(yǎng)基 (HM, Cat. #2301)
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