平滑肌細(xì)胞在動(dòng)脈疾病中起到重要作用。血管SMC切換到增殖表型的能力是血管疾病的發(fā)生和發(fā)展的主要因素之一。*近的研究表明SMC表達(dá)鈣離子通道、細(xì)胞間粘附分子（ICAM-1）、血管細(xì)胞粘附分子-1（VCAM-1）。ICAM-1和VCAM-1在SMC的表達(dá)可能有助于在血管壁的炎癥反應(yīng)，并可能參與血管疾病的進(jìn)展。血管平滑肌細(xì)胞在血管疾病研究中起到重要作用，可以被用來界定治療動(dòng)脈疾病新的治療靶標(biāo)。
Sciencell研究實(shí)驗(yàn)室的HASMC是從人主動(dòng)脈分離得到的，原代凍存，冰凍運(yùn)輸。每管細(xì)胞密度超過5×10^5/ml。細(xì)胞特性經(jīng)α-平滑肌肌動(dòng)蛋白和肌間線蛋白免疫熒光鑒定。本細(xì)胞經(jīng)檢測(cè)不含HIV-1、HBV、HCV、支原體、細(xì)菌、酵母菌和真菌。如采用ScienCell 實(shí)驗(yàn)室提供的實(shí)驗(yàn)條件，可保證此細(xì)胞15倍增增殖。

推薦培養(yǎng)基：平滑肌細(xì)胞培養(yǎng)基 (SMCM, Cat. #1101)

貨號(hào)	6110
產(chǎn)地	美國
縮寫	HASMC
規(guī)格	5 x 10^5 /1ml
用途	科研
儲(chǔ)存	液氮
運(yùn)輸	干冰
關(guān)鍵字	人主動(dòng)脈平滑肌細(xì)胞 HASMC 人主動(dòng)脈平滑肌細(xì)胞 HASMC 人主動(dòng)脈平滑肌細(xì)胞 HASMC 人主動(dòng)脈平滑肌細(xì)胞 HASMC 人主動(dòng)脈平滑肌細(xì)胞 HASMC 人主動(dòng)脈平滑肌細(xì)胞 HASMC 人主動(dòng)脈平滑肌細(xì)胞 HASMC 人主動(dòng)脈平滑肌細(xì)胞 HASMC
公司簡(jiǎn)介	合肥星肽生物科技有限公司作為專業(yè)的ScienCell中國代理商，專業(yè)經(jīng)營實(shí)驗(yàn)室科研用原代細(xì)胞、原代細(xì)胞專用培養(yǎng)基、原代細(xì)胞無血清培養(yǎng)基、干細(xì)胞、干細(xì)胞培養(yǎng)基、干細(xì)胞無血清培養(yǎng)基的研究和開發(fā)。合肥星肽生物科技有限公司始終致力于為客戶提供可靠的研究材料以及方便快捷的服務(wù)，對(duì)購買項(xiàng)目的前期資料提供,中期合同保證,后期貨物跟蹤到終售后的確保項(xiàng)目準(zhǔn)確到位，都有相關(guān)專業(yè)人士進(jìn)行維護(hù),確保您在合肥合肥星肽生物科技有限公司公司獲得上等服務(wù)！
聯(lián)系方式	何經(jīng)理，合肥星肽生物科技有限公司，Tel：0551-63802898 400-8702-898， E-mail：info@qingbio.com http://mails.js65k.cn QQ:514713116

1.) Guo T, Fang M, Zhang D, Li X. (2013) "Combination treatment with asiaticoside and rapamycin: A new hope for in?stent restenosis." ExpTher Med.6: 557

2.) Liu F, Zhong H, Liang JY, Fu P, Luo ZJ, Zhou L, Gou R, Huang J. (2010) "Effect of high glucose levels on the calcification of vascular smooth muscle cells by inducing osteoblastic differentiation and intracellular calcium deposition via BMP-2/Cbf?-1 pathway." J Zhejiang Univ Sci B. 11: 905-11.

3.) Xue JH, Yuan Z, Wu Y, Liu Y, Zhao Y, Zhang WP, Tian YL, Liu WM, Liu Y, Kishimoto C. (2010) "High glucose promotes intracellular lipid accumulation in vascular smooth muscle cells by impairing cholesterol influx and efflux balance." Cardiovasc Res. 86: 141-50.

4.) Geng J, Zhao Z, Kang W, Wang W, Liu G, Sun Y, Zhang Y, Ge Z. (2009) "Hypertrophic response to angiotensin II is mediated by protein kinase D-extracellular signal-regulated kinase 5 pathway in human aortic smooth muscle cells." Biochem Biophys Res Commun. 388: 517-22.

5.) Shin IS, Kim JM, Kim KL, Jang SY, Jeon ES, Choi SH, Kim DK, Suh W, Kim YW. (2009) "Early growth response factor-1 is associated with intraluminal thrombus formation in human abdominal aortic aneurysm." J Am Coll Cardiol. 53: 792-9.

6.) Heo SK, Yun HJ, Noh EK, Park WH, Park SD. (2008) "LPS induces inflammatory responses in human aortic vascular smooth muscle cells via Toll-like receptor 4 expression and nitric oxide production." Immunol Lett. 120: 57-64.

7.) Zhang X, Baughman CB, Kaplan DL. (2008) "In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth." Biomaterials. 29: 2217-27.

8.) Song Y, Qi H, Wu C. (2007) "Effect of 1,25-(OH)2D3 (a vitamin D analogue) on passively sensitized human airway smooth muscle cells." Respirology. 12: 486-94.